

There are many cases where the COVID-19 infection has taken more than 14 days to present any symptoms ( Fan et al., 2020 Huang et al., 2020). COVID-19 has an incubation period of 1–14 days, but typically, it takes 3–7 days to present symptoms. However, a large proportion of infected patients remain asymptomatic ( Lovato et al., 2020 Rodriguez-Morales et al., 2020). It has a wide range of symptoms like fever, dry cough, shortness of breath, muscle pain, fatigue, sore throat, ageusia, and anosmia.

COVID-19 affects people in different ways. It causes coronavirus disease 2019 (COVID-19) ( Long et al., 2020 Wang et al., 2021). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged from Wuhan, China in December 2019 has posed a great threat to global public health. No association was found between blood groups and susceptibility to severity of disease and mortality. Blood group A (odds ratio, 1.53 CI, 1.40–1.66 p < 0.001) and B (odds ratio, 1.15 CI, 1.06–1.24 p < 0.001) is observed to be significantly associated with COVID-19 susceptibility, whereas blood group O (odds ratio, 0.65 CI, 0.59–0.71 p < 0.001) and AB (odds ratio, 0.66 CI, 0.59–0.71 p < 0.001) have low risk of COVID-19 infection.Ĭonclusion: A, B, and Rh+ are found to be more susceptible to COVID-19 infection, whereas blood groups O, AB, and Rh− are at a lower risk of COVID-19 infection.

Of the patients, 98.07% were Rh positive. Results: In the 2,586 COVID-19-infected patients, the frequencies of A, B, O, and AB were 29.93%, 41.80%, 21.19%, and 7.98%, respectively. Data was analyzed using chi-square test, odds ratio, and Mann–Whitney test to determine the association of blood groups. Patients were enrolled from Apto October 4, 2020. A total of 2,586 real-time PCR (RT-PCR)-confirmed coronavirus disease 2019 (COVID-19) patients were recruited. We investigated the association of ABO and Rh blood groups with susceptibility to coronavirus disease 2019 infection, severity of disease, recovery period, and mortality of patients. Methods: This is a single-center, retrospective study conducted at Sir Ganga Ram Hospital, Delhi. Studies have shown association of blood groups A and O with higher and lower odds for coronavirus disease 2019 positivity, respectively. 2Department of Blood Transfusion Medicine, Sir Ganga Ram Hospital, New Delhi, Indiaīackground: ABO and Rh blood group systems are associated with many diseases including cancerous, infectious, non-infectious, bacterial and viral diseases.1Department of Research, Sir Ganga Ram Hospital, New Delhi, India.Rashmi Rana 1*†, Vivek Ranjan 2† and Naveen Kumar 1†
